Keywords
Vascular System Lesions
Hemangioma
How to Cite
Abstract
Vascular lesions comprise a group of entities that are sometimes confused in terms of definitions and terms. It is common that health staff does not use the same nomenclature to refer to these injuries, which might lead to errors or misinterpretation. The present paper intends to harmonize concepts based on the existing classification of vascular lesions provided by the International Society for the Study of Vascular Anomalies (ISSVA). This Society split them into two large groups: vascular tumors (abnormal cell proliferation) and vascular malformations (abnormalities in the architecture of the vascular endothelium). They describe the characteristics of infantile hemangioma, congenital hemangioma, kaposiform hemangioendothelioma and tufted angioma. They differ in their clinical, imagenaegenological, histological, prognostic and therapeutic characteristics. Treatment can be simple or complex and it must be adjusted to every patient, which is why they are approached by a multidisciplinary team ideally made up of a pediatric surgeon, vascular surgeon, interventional imaging specialist, dermatologist, plastic surgeon, among other specialists, who know the pathologies and have proper management of them.
References
Alfageme F, Salgüero I, Zamanta F, Roustán G. Actualización en ecografía de las anomalías vasculares. Actas Dermo-Sifiliogr 2016; 107(4):284-93. doi: 10.1016/j.ad.2015.11.004.
International Society for the Study of Vascular Anomalies. ISSVA classification for vascular anomalies. Approved at the 20th ISSVA Workshop, Melbourne, April 2014, last revision May 2018. Disponible en: https://www.issva.org/UserFiles/file/ISSVA-Classification-2018.pdf. (Consulta: 26 abril 2024).
Leon J, Kangesu L. Understanding vascular anomalies: a common language for doctors. Surgery 2012; 30(8):427-34.
Wassef M, Blei F, Adams D, Alomari A, Baselga E, Berenstein A, et al. Vascular anomalies classification: recommendations from the International Society for the Study of Vascular Anomalies. Pediatrics 2015; 136(1):e203-14. doi: 10.1542/peds.2014-3673.
López R, López J, Belendez C, Herrero A, Mateos M, Ramírez G. Tumores vasculares en la infancia. An Pediatr (Barc) 2010; 72(2): 143.e1-15.
Baselga E, Bernabéu J, van Esso D, Febrer M, Carrasco Á, de Lucas R, et al. Consenso español sobre el hemangioma infantil. An Pediatr (Barc) 2016; 85(5):256-65. doi: 10.1016/j.anpedi.2015.10.004.
Ballah D, Cahill A, Fontalvo L, Yan A, Treat J, Low D, et al. Vascular anomalies: what they are, how to diagnose them, and how to treat them. Curr Probl Diagn Radiol 2011; 40(6):233-47. doi: 10.1067/j.cpradiol.2011.04.001.
Goldenberg D, Hiraki P, Marques T, Koga A, Gemperli R. Surgical treatment of facial infantile hemangiomas: an analysis based on tumor characteristics and outcomes. Plast Reconstr Surg 2016; 137(4):1221-31. doi: 10.1097/PRS.0000000000002016.
Keller R, Patel K. Evidence-based medicine in the treatment of infantile hemangiomas. Facial Plast Surg Clin North Am 2015; 23(3):373-92. doi: 10.1016/j.fsc.2015.04.009.
Bénateau H, Labbé D, Dompmartin A, Boon L. Place de la chirurgie dans les hémangiomes au stade des séquelles. Ann Chir Plast Esthet 2006; 51(4-5):330-8. doi: 10.1016/j.anplas.2006.07.005.
Nasseri E, Piram M, McCuaig C, Kokta V, Dubois J, Powell J. Partially involuting congenital hemangiomas: a report of 8 cases and review of the literature. J Am Acad Dermatol 2014; 70(1):75-9. doi: 10.1016/j.jaad.2013.09.018.
Lee P, Frieden I, Streicher J, McCalmont T, Haggstrom A. Characteristics of noninvoluting congenital hemangioma: a retrospective review. J Am Acad Dermatol 2014; 70(5):899-903. doi: 10.1016/j.jaad.2014.01.860.
Fernández Y, Bernabeu M, García J. Kaposiform hemangioendothelioma. Eur J Intern Med 2009; 20(2):106-13. doi: 10.1016/j.ejim.2008.06.008.
Drolet B, Trenor C, Brandão L, Chiu Y, Chun R, Dasgupta R, et al. Consensus-derived practice standards plan for complicated Kaposiform hemangioendothelioma. J Pediatr 2013; 163(1):285-91. doi: 10.1016/j.jpeds.2013.03.080.
Inguanzo M, Piqué E, Aparicio J, Vaca M. Hemangioendotelioma kaposiforme con fenómeno de Kasabach-Merritt. An Pediatr (Barc) 2018; 88(5):292-3. doi: 10.1016/j.anpedi.2017.11.006.
Giachetti A, Cordisco M. Anomalías vasculares. En: Larralde M, Abad E, Luna P, Boggio P, Ferrari B. Dermatología pediátrica. 3 ed. Buenos Aires: Ediciones Journal, 2021:448.
Tlougan B, Lee M, Drolet B, Frieden I, Adams D, Garzon M. Medical management of tumors associated with Kasabach-Merritt phenomenon: an expert survey. J Pediatr Hematol Oncol 2013; 35(8):618-22. doi: 10.1097/MPH.0b013e318298ae9e.
Schmid I, Klenk A, Sparber M, Koscielniak E, Maxwell R, Häberle B. Kaposiform hemangioendothelioma in children: a benign vascular tumor with multiple treatment options. World J Pediatr 2018; 14(4):322-9. doi: 10.1007/s12519-018-0171-5.
Hammill A, Wentzel M, Gupta A, Nelson S, Lucky A, Elluru R, et al. Sirolimus for the treatment of complicated vascular anomalies in children. Pediatr Blood Cancer 2011; 57(6):1018-24. doi: 10.1002/pbc.23124.
Ji Y, Chen S, Yang K, Xia C, Li L. Kaposiform hemangioendothelioma: current knowledge and future perspectives. Orphanet J Rare Dis 2020; 15(1):39. doi: 10.1186/s13023-020-1320-1.
Instituto Nacional del Cáncer. Hemangioendotelioma kaposiforme. Publicación del 2 de agosto de 2023. Disponible en: https://www.cancer.gov/pediatric-adult-rare-tumor/espanol/tumores-raros/tumores-vasculares-raros/hemangioendotelioma-kaposiforme. (Consulta: 11 diciembre 2023).
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2025 Archives of Pediatrics of Uruguay